This in vitro fertilisation treatment with egg donor also includes the genetic study of the embryos, that is, the pre-implantation genetic screening technique, to offer a unified, more comfortable and easier treatment with greater chances of success and peace of mind, always without risks for the mother.
In the case of the egg, the age of the woman is a determining factor of the quality thereof but since they are donor eggs, they are better quality and have fewer alterations in their chromosomes.
This technique would be used when it is suspected that the cause of the failed implantation or the miscarriage lies in the sperm cell. We could, therefore, detect genetic (chromosome) alterations in the embryos and transfer to the uterus the free embryos thereof, improving the results and reducing the risk of miscarriage.
What does IVF with donor eggs and pre-implantation genetic screening consist of, step by step?
1. The process begins with the donor-recipient selection and assignment.
2. The donated eggs will be fertilised to produce embryos.
3. These will be developed in the laboratory in a completely controlled environment.
4. Between the third and fifth day of life of the embryos, the obtainment of the embryonic material necessary for the genetic study (a small sample is extracted) will be performed.
5. The embryos will be cryopreserved until the genetic analysis indicates which of them are free of chromosome alterations.
6. In a subsequent cycle, the endometrium of the woman is prepared so that it is receptive and the embryo/s is/are devitrified for their transfer.
The other frozen embryos with no anomalies are kept in this state.